Intracranial aneurysms (IAs) are oblate- or prolate-shaped dilations of brain arterial vessels that are prevalent in about 3% of the adult population. If an IA ruptures, an aneurysmal subarachnoid haemorrhage develops, with a high risk for permanent disability or fatal outcome [1]. Therefore, effective treatment of unruptured IA is essential to ensure disruption of the inflow and prevent rupture. Endovascular treatments include placement of flow-modulating devices (FMDs) such as coils (CO), flow diverter (FD), woven endo-bridge (WEB), and most recently, Contour (CNT), which assures either intrasaccular flow disruption (CO, WEB, and CNT) or intravascular flow diversion (FD). Shape-memory materials, such as Nitinol, are used in these devices to enable crimping for catheter delivery and self-expansion at the aneurysm site. FMDs reduce blood flow into IA and facilitate healing. The efficiency of FMDs can be studied using in silico biomechanical structural models and homogenized poro-elastic approximations, which are used to predict the fully resolved velocity field simulations of the blood flow using advanced numerical approaches such as the Lattice Boltzmann Methods for the incompressible Navier-Stokes equations and patient-specific IA geometries. In addition, in vitro studies can be used to assess the performance of FMDs [3]. However, there is still a research gap in the interdisciplinary perspectives and joint ventures to tackle this crucial biomedical problem. This mini-symposium aims to highlight the recent developments, ongoing challenges, and prospects in the biomechanical modeling, 3D-printing, and flow dynamics of these endovascular devices for patient-specific IAs. [1] J. L. Brisman et al., Cerebral aneurysms, The New England Journal of Medicine 355, 9 (2006) 928-939. [2] M. Frank et al., Numerical simulation of endovascular treatment options for cerebral aneurysms, Annals of 3D Printed Medicine 47, 3 (2024) e202370007. [3] M. S. Pravdivtseva et al., The effect of the size of the new contour neurovascular device for altering intraaneurysmal flow, Interventional Neuroradiology 31, 1 (2023) 49-56.