In recent years, the performance requirements for mechanical structures have been increasing, and expectations for the industrial application of topology optimization, one of the optimal design methods, have been rising. However, to apply it to actual product design, it is essential to consider complex physical phenomena such as multi-physics, transient response, and material nonlinearity. Furthermore, optimization methods that incorporate manufacturability and economic feasibility are required, making it　indispensable to take a multidisciplinary design perspective rather than focusing on a single design domain. This mini-symposium focuses on topology optimization for multidisciplinary design and aims to discuss cutting-edge methodologies with industrial applications in mind. We broadly invite research presentations on methods incorporating advanced analyses such as multi-physics, transient response, and material nonlinearity, as well as designs that consider manufacturing constraints and economic feasibility, and optimization through interdisciplinary integration.