In this study, we adopt a dislocation density-based crystal plasticity model coupled with an elasto-plastic phase-field damage framework to evaluate the fracture behavior of metals under various loading conditions. The approach is applied to multiple case studies, including single crystal tensile test specimens, void growth and nucleation due to external particles, and fatigue loading scenarios. Direct comparisons with experimental findings are conducted to analyze the strengths and limitations of phase-field modeling in capturing ductile fracture mechanisms. The results demonstrate the model's capability to investigate practical applications related to advanced manufacturing and materials for extreme environments. However, the study also highlights key limitations of phase-field damage modeling for ductile fracture, emphasizing the need for careful consideration when applying this approach to complex material systems. SNL is managed and operated by NTESS under DOE NNSA contract DE-NA0003525.SAND2026-16427A.