The use of Active Mass Dampers (AMDs) has been widely investigated for framed structures, where their effectiveness can be reliably evaluated within linear dynamic analysis[1]. Conversely, their application to masonry structures remains largely unexplored, mainly due to the intrinsic material heterogeneity, limited tensile capacity, and strongly nonlinear response under seismic loading. This study aims to investigate the feasibility and effectiveness of AMD systems applied to masonry structures, with particular emphasis on the interaction between active control devices and non-classical damping. The research focuses on the development of suitable numerical models capable of capturing the non-proportional damping characteristics and the evolving fracture framework. The performance of AMDs is evaluated through nonlinear time-history analyses, considering both the control efficiency and the robustness of the system under increasing damage levels. Masonry is treated as a complex material, whose macroscopic dynamic behavior is strongly influenced by damage mechanisms and cracking patterns. The expected outcome of this research is to provide insight into the potential and limitations of active control techniques for masonry structures, contributing to the development of advanced seismic protection strategies for existing and heritage constructions, and supporting the design and optimization of engineered control systems interacting with complex materials.